Effect of gonadotrophin therapy on testicular volume and sexual development in adolescent boys with hypogonadotrophic hypogonadism.

These patients may not have shown excessive growth during early childhood as observed by Aceto et al. (1966). After therapy was stopped, 2 cases showed the expected adrenal overactivity (high urinary 17KS). Treatment must, therefore, be continued. The present management for all types of congenital adrenal hyperplasia was recently reviewed (Raiti and Newns, 1970). The criteria for diagnosis have not altered (Raiti and Newns, 1964).